Verrucas and common warts in pharmacy practice: recognition and risk assessment

Verrucas are plantar warts caused by infection with the human papillomavirus (HPV). They develop on the soles of the feet or toes, typically in weight-bearing areas exposed to pressure or friction 1,2.

In community pharmacy, patients may seek advice due to discomfort, uncertainty about the diagnosis, or concerns about persistence and spread.

Recognizing verrucas

Typical features include:

Because of their location, verrucas may interfere with walking and daily activities, prompting patients to seek advice early.

Understanding common warts

Common warts are hyperkeratotic skin growths that usually occur on the hands, fingers, or other non-weight-bearing areas 1.

They typically:

Although medically benign, common warts may cause cosmetic concern or anxiety about transmission, particularly when lesions are visible or multiple.

Natural course of verrucas and warts

In immunocompetent individuals, verrucas and warts may resolve spontaneously as the immune system develops a response to HPV. However, clearance is unpredictable and may take months or several years 3. During this time, lesions can persist, spread to other areas, or be transmitted to others. Understanding the natural history of HPV-related lesions supports appropriate patient counselling, including explanation of persistence, recurrence, and variability in treatment response 2-4.

How infection spreads

HPV thrives in environments that promote skin maceration and microtrauma 1, 5.

Transmission is more likely through:

The presence of broken or softened skin increases susceptibility to infection.

Patients at increased risk

Anyone can develop verrucas or common warts; however, they are more frequently observed in 1, 5:

In immunocompromised patients, lesions may be more extensive, persistent, or atypical and warrant closer assessment 6.

When to consider referral

Referral to a general practitioner or dermatologist may be appropriate when:

Early identification of higher-risk patients supports appropriate onward care.

The pharmacist’s role

Pharmacists play an important role in recognising the characteristic symptom pattern of plantar fasciitis, reassuring patients about the nature of the condition, and guiding them toward appropriate next steps, including conservative care and referral when needed.

💡 Clinical distinction: verrucas vs common warts

Verrucas and common warts are caused by the same virus (HPV). The key clinical difference lies in their location and associated symptoms. Verrucas develop on weight-bearing areas of the foot and may cause pain on walking, whereas common warts typically occur on the hands and are rarely painful.

Resources

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Managing warts and verrucas: a practical guide for pharmacists

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From balance to breakdown: The physiology of plantar skin

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Common Foot Care Myths Patients Believe

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  1. Witchey, D.J., et al., Plantar Warts: Epidemiology, Pathophysiology, and Clinical Management. J Am Osteopath Assoc, 2018. 118(2): p. 92-105.
  2. Garcia-Oreja, S., et al., Topical treatment for plantar warts: A systematic review. Dermatol Ther, 2021. 34(1): p. e14621.
  3. Bruggink, S.C., et al., Natural course of cutaneous warts among primary schoolchildren: a prospective cohort study. Ann Fam Med, 2013. 11(5): p. 437-41.
  4. Kwok, C.S., et al., Topical treatments for cutaneous warts. Cochrane Database Syst Rev, 2012. 2012(9): p. CD001781.
  5. Sterling, J.C., et al., British Association of Dermatologists’ guidelines for the management of cutaneous warts 2014. Br J Dermatol, 2014. 171(4): p. 696-712.
  6. D’Souza, G.F. and J.E. Zins, Severe Plantar Warts in an Immunocompromised Patient. N Engl J Med, 2017. 377(3): p. 267.


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